Deficiency in which vitamin can primarily lead to night blindness?

Night blindness is primarily associated with a deficiency of Vitamin A. This vitamin plays a crucial role in maintaining healthy vision, specifically in low-light conditions. It is a component of rhodopsin, a protein in the eyes that enables the conversion of light into electrical signals that the brain can interpret as visual images. When Vitamin A levels are insufficient, the production of rhodopsin is impaired, leading to difficulties in seeing at night or in dim light, which is known as night blindness.

In contrast, deficiencies in Vitamin B are typically linked to various metabolic and neurological issues, while Vitamin C is essential for collagen synthesis and immune function but is not directly related to vision. Vitamin D is primarily involved in calcium metabolism and bone health, with no specific role in the eye's ability to adjust to darkness. Thus, Vitamin A deficiency directly correlates with the impairment of vision ability in low-light conditions, making it the correct answer for this question.